Celebrities like Priyanka Chopra and David Beckham announced honorees including Edward Enninful, Aurora James, Stella McCartney and more.
Plus, Hilton Als explores Grace Wales Bonner's elegant vision of Black style.
"I'm trying more to focus not on what we already know are the problems, but what are we doing to solve them?" says Serre.
For the first time, a single designer took home the night's two top honors.
See the full list of winners right this way.
London will celebrate its version of the CFDA Awards in a ceremony on Nov. 23.